Anti-Hu CD75 PE
CD75 is a lactosamine structure, which is present mainly on the surface of germinal center B cells. With lower level it is present on other mature B cells, and it is downregulated during differentiation to plasma cells. It is a marker which differentiates between malignant B cell types.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Stimulated human PBL
Target Antigen
CD75
Clone
LN1
Applications
FC (QC tested)
Format
PE
Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
References & Citations
*Fromm JR, Thomas A, Wood BL: Characterization and purification of neoplastic cells of nodular lymphocyte predominant hodgkin lymphoma from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Pathol. 2017 Feb;187 (2) :304-317., URL: https://pubmed.ncbi.nlm.nih.gov/27998726/, *Epstein AL, Marder RJ, Winter JN, Fox RI: Two new monoclonal antibodies (LN-1, LN-2) reactive in B5 formalin-fixed, paraffin-embedded tissues with follicular center and mantle zone human B lymphocytes and derived tumors. J Immunol. 1984 Aug;133 (2) :1028-36., URL: https://pubmed.ncbi.nlm.nih.gov/6376628/, *Virtanen S, Schulte R, Stingl J, Caldas C, Shehata M: High-throughput surface marker screen on primary human breast tissues reveals further cellular heterogeneity. Breast Cancer Res. 2021 Jun 13;23 (1) :66., URL: https://pubmed.ncbi.nlm.nih.gov/34120626/
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody LN1 recognizes CD75, a lactosamine structure present mainly on the surface of B cell types.
Applications Notes
6
Isotype
Mouse IgM kappa
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