β-Endorphin, human
Product Specifications
UNSPSC Description
β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibits antinociception activity.
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_beta_-Endorphin,_human.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Smiles
OC(C=C1)=CC=C1CC(N)C(NCC(NCC(NC(CC2=CC=CC=C2)C(N[C@H](CCSC)C(NC(C(O)C)C(N[C@H](CO)C(NC(CCC(O)=O)C(N[C@H](CCCCN)C(NC(CO)C(NC(CCC(N)=O)C(NC(C(O)C)C(N3[C@@H](CCC3)C(NC(CC(C)C)C(NC(C(C)C)C(NC(C(O)C)C(NC(CC(C)C)C(NC(C(NC(CCCCN)C(NC(CC(N)=O)C(NC(C)C(NC(C(C)CC)C(NC(C(C)CC)C(NC(CCCCN)C(NC(CC(N)=O)C(NC(C)C(NC(C(NC(CCCCN)C(NC(CCCCN)C(NCC(NC(C(O)=O)CCC(O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
3464.98
References & Citations
[1]Narita M, et al. Evidence for the existence of the beta-endorphin-sensitive "epsilon-opioid receptor" in the brain: the mechanisms of epsilon-mediated antinociception. Jpn J Pharmacol. 1998 Mar;76(3):233-53.|[2]Luan YH, et al. Action of β-endorphin and nonsteroidal anti-inflammatory drugs, and the possible effects of nonsteroidal anti-inflammatory drugs on β-endorphin. J Clin Anesth. 2017 Feb;37:123-128.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1502/β-Endorphin-human-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1502/β-Endorphin-human-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
61214-51-5
Available Sizes
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