PKA Inhibitor (5-24)

<strong>PKA Inhibitor (5-24)</strong>_x000D_ <strong>Catalog number:</strong> B2017239_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 500 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 2222.4_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid, 2,2,2-trifluoroacetate Salt, PKI (5-24), Protein Kinase A Inhibitor (5-24)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Guergnon J, Dessauge F, Traincard F, Cayla X, Rebollo A, Bost PE, Langsley G, Garcia A. A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes Apoptosis. 2006 Aug;11(8):1263-73._x000D_ 2: Padilla A, Hauer JA, Tsigelny I, Parello J, Taylor SS. Solution structure of synthetic peptide inhibitor and substrate of cAMP-dependent protein kinase. A study by 2D H NMR and molecular dynamics J Pept Res. 1997 Mar;49(3):210-20._x000D_ 3: Harrison DA, Carr DW, Meizel S. Involvement of protein kinase A and A kinase anchoring protein in the progesterone-initiated human sperm acrosome reaction Biol Reprod. 2000 Mar;62(3):811-20._x000D_ 4: Hayabuchi Y, Davies NW, Standen NB. Angiotensin II inhibits rat arterial KATP channels by inhibiting steady-state protein kinase A activity and activating protein kinase Ce J Physiol. 2001 Jan 15;530(Pt 2):193-205._x000D_ 5: Melamed P, Gur G, Elizur A, Rosenfeld H, Sivan B, Rentier-Delrue F, Yaron Z. Differential effects of gonadotropin-releasing hormone, dopamine and somatostatin and their second messengers on the mRNA levels of gonadotropin II beta subunit and growth hormone in the teleost fish, tilapia Neuroendocrinology. 1996 Oct;64(4):320-8._x000D_ 6: Hilário-Souza E, Valverde RH, Britto-Borges T, Vieyra A, Lowe J. Golgi membranes from liver express an ATPase with femtomolar copper affinity, inhibited by cAMP-dependent protein kinase Int J Biochem Cell Biol. 2011 Mar;43(3):358-62._x000D_ 7: Schurov IL, Hepworth TJ, Hastings MH. Dopaminergic signalling in the rodent neonatal suprachiasmatic nucleus identifies a role for protein kinase A and mitogen-activated protein kinase in circadian entrainment Eur J Neurosci. 2002 Jan;15(2):223-32._x000D_ 8: Johnson BD, Brousal JP, Peterson BZ, Gallombardo PA, Hockerman GH, Lai Y, Scheuer T, Catterall WA. Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase J Neurosci. 1997 Feb 15;17(4):1243-55._x000D_ 9: Wörner R, Lukowski R, Hofmann F, Wegener JW. cGMP signals mainly through cAMP kinase in permeabilized murine aorta Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H237-44._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9045648">10: Gray PC, Tibbs VC, Catterall WA, Murphy BJ. Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels J Biol Chem. 1997 Mar 7;272(10):6297-302. </a>_x000D_ _x000D_ <strong>Products Related to PKA Inhibitor (5-24) can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>