PDI-IN-2
PDI-IN-2 (Compound 22) is a PDI or recombinant PDI inhibitor with IC50 values of 0.62 and 0.63 μM, respectively. PDI-IN-2 has antitumor activity[1].
Product Specifications
UNSPSC
12352005
Target
PDI
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pdi-in-2.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C(C(C=C(C2=O)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3OC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)=O)=CC=C1
Molecular Formula
C24H24O13
Molecular Weight
520.44
References & Citations
[1]Juang YP, et al. Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition. J Med Chem. 2024 Feb 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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