Agaritine
Agaritine is a compound isolated from the commonly cultivated commercial mushroom Agaricus bisporus. Agaritine is hydrolyzed by an enzyme system present in the mushroom into 4- (hydroxymethyl) benzenediazonium ion, which is a carcinogen in mice. Agaritine is structurally similar to some known carcinogens and can be used for research in cancer and food safety[1][2].
Product Specifications
CAS Number
2757-90-6
UNSPSC
12352005
Target
HIV Protease
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/agaritine.html
Smiles
OC([C@@H](N)CCC(NNC1=CC=C(CO)C=C1)=O)=O
Molecular Formula
C12H17N3O4
Molecular Weight
267.28
References & Citations
[1]Ross A E, et al. Evidence for the occurrence and formation of diazonium ions in the Agaricus bisporus mushroom and its extracts[J]. Journal of agricultural and food chemistry, 1982, 30 (3) : 521-525.|[2]Ross A E, et al. Occurrence, stability and decomposition of beta-N [gamma-L (+) -glutamyl]-4-hydroxymethylphenylhydrazine (agaritine) from the mushroom Agaricus bisporus[J]. Food and Chemical Toxicology: an International Journal Published for the British Industrial Biological Research Association, 1982, 20 (6) : 903-907.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Phase 1
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