8-Br-NHD+

8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog[1].

Product Specifications

CAS Number

[477782-33-5]

Product Name Alternative

Nicotinamide 8-Br-hypoxanthine dinucleotide

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/8-br-nhd.html

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CNC3=O)O[C@@H]1COP(OP(OC[C@H]4O[C@@H]([N+]5=CC=CC(C(N)=O)=C5)[C@H](O)[C@@H]4O)([O-])=O)(O)=O

Molecular Formula

C21H25BrN6O15P2

Molecular Weight

743.31

References & Citations

[1]Wagner G K, et al. Analogues of cyclic adenosine 5′-diphosphate ribose and adenophostin A, nucleotides in cellular signal transduction[C]//Nucleic acids symposium series. Oxford University Press, 2003, 3 (1) : 1-2.