8-Br-NHD+
8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog[1].
Product Specifications
CAS Number
477782-33-5
Product Name Alternative
Nicotinamide 8-Br-hypoxanthine dinucleotide
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-br-nhd.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CNC3=O)O[C@@H]1COP(OP(OC[C@H]4O[C@@H]([N+]5=CC=CC(C(N)=O)=C5)[C@H](O)[C@@H]4O)([O-])=O)(O)=O
Molecular Formula
C21H25BrN6O15P2
Molecular Weight
743.31
References & Citations
[1]Wagner G K, et al. Analogues of cyclic adenosine 5′-diphosphate ribose and adenophostin A, nucleotides in cellular signal transduction[C]//Nucleic acids symposium series. Oxford University Press, 2003, 3 (1) : 1-2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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