Ceftiofur (sodium)
Ceftiofur sodium is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur sodium exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur sodium also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6[1][2][3].
Product Specifications
CAS Number
104010-37-9
Product Name Alternative
Sodium ceftiofur
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial; Interleukin Related; NF-κB; p38 MAPK; TNF Receptor
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Ceftiofur-sodium.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O[Na])C(N12)=C(CSC(C3=CC=CO3)=O)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O
Molecular Formula
C19H16N5NaO7S3
Molecular Weight
545.54
Precautions
H317, H334
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Available Sizes
Frequently Asked Questions
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