Bim-IN-1
Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity[1].
Product Specifications
CAS Number
2909483-36-7
Product Name Alternative
MK-591
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bim-in-1.html
Purity
99.57
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
FC1=CC(C2N(S(=O)(CC3=CC=C(Cl)C=C3Cl)=O)CCCCC2)=CC=C1
Molecular Formula
C19H20Cl2FNO2S
Molecular Weight
416.34
References & Citations
[1]Richards BJ, et al. Discovery, synthesis and exploration of N-benzylsulfonyl-2-phenylazepanes as inhibitors of Bim expression in a mouse embryonic fibroblast model. Bioorg Chem. 2022; 120:105635.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bim
Available Sizes
Frequently Asked Questions
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