PDE7-IN-4
PDE7-IN-4 is a phosphodiesterase 7 (PDE7) inhibitor with activity that increases intracellular cyclic adenosine monophosphate (cAMP) levels. PDE7-IN-4 shows potential inhibitory effects in neurotransmission and anti-inflammatory applications. PDE7-IN-4 exerts its biological activity by acting on the cAMP/cAMP response element binding protein (CREB) pathway. The development of PDE7-IN-4 aims to improve its pharmacokinetic characteristics to more effectively target neurodegenerative diseases and other inflammation-related diseases[1].
Product Specifications
CAS Number
[18741-24-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde7-in-4.html
Purity
98.55
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
S=C(N1)N(C2=CC=CC=C2)C(C3=C1C=CC=C3)=O
Molecular Formula
C14H10N2OS
Molecular Weight
254.31
Precautions
H315, H319, H335
References & Citations
[1]Improved Controlled Release and Brain Penetration of the Small Molecule S14 Using PLGA Nanoparticles
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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