Fosdagrocorat
Fosdagrocorat (PF-04171327) is a dissociated glucocorticoid receptor agonist.
Product Specifications
CAS Number
[1044535-58-1]
Product Name Alternative
PF-04171327
UNSPSC
12352005
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Fosdagrocorat.html
Purity
98.70
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FC(F)(F)[C@]1(OP(O)(O)=O)C[C@]2([H])[C@](C3=CC=C(C(NC(C=CC=N4)=C4C)=O)C=C3CC2)(CC1)CC5=CC=CC=C5
Molecular Formula
C29H30F3N2O5P
Molecular Weight
574.53
References & Citations
[1]Miyoshi S, et al. Pharmacokinetics and food-effect of fosdagrocorat (PF-04171327), a dissociated agonist of the glucocorticoid receptor, in healthy adult Caucasian and Japanese subjects. Int J Clin Pharmacol Ther. 2016 Dec;54 (12) :966-976.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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