PM54
Product Specifications
UNSPSC Description
PM54 is a lurbinectedin (HY-16293) derivative. PM54 exhibits potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pm54.html
Solubility
10 mM in DMSO
Smiles
OCC1N[C@](C(OC2)=O)(CS[C@H]3[C@]4([H])N([C@@H](O)[C@H]5N(C)[C@@H]4C6=C(C=C(C)C(OC)=C6O)C5)[C@@H]2C7=C3C(OC(C)=O)=C(C)C8=C7OCO8)C9=C(C(C=CC=C%10)=C%10O9)C1
Molecular Weight
785.86
References & Citations
[1]Cigrang M, et al. Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription. bioRxiv, 2024: 2024.03. 26.586754.
Shipping Conditions
Room temperature
Clinical Information
Phase 1
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