Indeno[1,2,3-cd]pyrene

Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor[1][2].

Product Specifications

CAS Number

[193-39-5]

UNSPSC

12352005

Hazard Statement

H351

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/indeno-1-2-3-cd-pyrene.html

Purity

99.66

Smiles

C12=C3C(C4=C2C=CC=C4)=CC5=CC=CC6=CC=C(C3=C56)C=C1

Molecular Formula

C22H12

Molecular Weight

276.33

Precautions

H351

References & Citations

[1]Ke S, et al. An in vitro cytotoxicities comparison of 16 priority polycyclic aromatic hydrocarbons in human pulmonary alveolar epithelial cells HPAEpiC. Toxicol Lett. 2018 Jun 15;290:10-18. |[2]Wong TH, et al. A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor. Sci Rep. 2018 Mar 26;8 (1) :5198.