RAC3 Recombinant Rabbit Monoclonal Antibody [JE56-48]
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Ras-related C3 botulinum toxin substrate 3 p21-Rac3 RAC3
Swiss Prot
P60763 Human, P60764 Mouse
Cellular Locus
Cytoplasm, Endomembrane system, Cell projection, lamellipodium, Cytoplasm, perinuclear region, Cell membrane, cytoskeleton.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human RAC3 aa 71-170 / 192.
Isotype
IgG
Clone
JE56-48
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HEK-293 cell lysate, JAR cell lysate, HUVEC cell lysate, PC-12 cell lysate, SH-SY5Y cell lysate, C2C12 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 21 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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