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BW A575C

BW A575C is a dual inhibitor against angiotensin converting enzyme (ACE) and β-adrenoceptor. BW A575C produces a competitive blockade of Isoprenaline -induced tachycardia in a guinea-pig right atrial. BW A575C also inhibits Angiotensin I (HY-P1032) -induced pressor responses in rats. BW A575C is promising for research of hypertensive diseases[1].

Product Specifications

CAS Number

103221-88-1

UNSPSC

12352005

Target

Adrenergic Receptor; Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bw-a575c.html

Smiles

CC(C)NCC(O)COC1=C2C(NC(C(NCCCCC(C(O)=O)NC(C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=C2)=CC=C1

Molecular Formula

C29H43N5O8

Molecular Weight

589.68

References & Citations

[1]Allan G, et al. BW A575C, a chemically novel agent with angiotensin converting enzyme inhibitor and beta-adrenoceptor-blocking properties. Br J Pharmacol. 1987 Mar;90 (3) :609-15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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