Rheumatoid Factor Removal Kit for Serum and Plasma

<strong>Rheumatoid Factor Removal Kit for Serum and Plasma</strong>_x000D_ <strong>Catalog number:</strong> K2010013_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Size:</strong> 10 reactions (enough for processing 10 samples of 1 mL each)_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Supplied as:</strong> Ready-to-use kit_x000D_ _x000D_ <strong>Applications:</strong> Rheumatoid Factor (RF) remains a major source of interference in immunoassays (despite claims to the contrary made by manufacturers). Using a propriety solution, this kit is designed to deplete human serum or plasma from Rheumatoid Factor. Simply add serum or plasma to the provided solution, vortex, spindown and recover an RF-free sample. For Research Use Only. Not for diagnostic use._x000D_ _x000D_ <strong>Keywords</strong>: RF Depletion Kit, RF Removal Kit, RF Suppression Kit, RF Blocking_x000D_ _x000D_ <strong>References:</strong>_x000D_ _x000D_ 1: Maibom-Thomsen SL, Trier NH, Holm BE, Hansen KB, Rasmussen MI, Chailyan A,_x000D_ Marcatili P, Højrup P, Houen G. Immunoglobulin G structure and rheumatoid factor_x000D_ epitopes. PLoS One. 2019 Jun 14;14(6):e0217624._x000D_ _x000D_ 2: Shmerling RH, Delbanco TL. The rheumatoid factor: an analysis of clinical_x000D_ utility. Am J Med. 1991 Nov;91(5):528-34._x000D_ _x000D_ 3: Kalsi J, Isenberg D. Rheumatoid factor: primary or secondary event in the_x000D_ pathogenesis of RA? Int Arch Allergy Immunol. 1993;102(3):209-15._x000D_ _x000D_ 4: Johnson PM, Faulk WP. Rheumatoid factor: its nature, specificity, and_x000D_ production in rheumatoid arthritis. Clin Immunol Immunopathol. 1976_x000D_ Nov;6(3):414-30._x000D_ _x000D_ 5: Beduleva L, Stolyarova E, Sidorov A, Khramova T, Terentiev A, Menshikov I,_x000D_ Abisheva N, Snigiryev A, Fomina K. Immunoglobulin G amplifies the production of_x000D_ regulatory rheumatoid factor in vitro through idiotype-anti-idiotype_x000D_ interactions. J Immunoassay Immunochem. 2020;41(2):219-230._x000D_ _x000D_ 6: Eichenfield AH, Athreya BH, Doughty RA, Cebul RD. Utility of rheumatoid_x000D_ factor in the diagnosis of juvenile rheumatoid arthritis. Pediatrics. 1986_x000D_ Sep;78(3):480-4._x000D_ _x000D_ 7: Chinnadayyala SR, Park J, Abbasi MA, Cho S. Label-free electrochemical_x000D_ impedimetric immunosensor for sensitive detection of IgM rheumatoid factor in_x000D_ human serum. Biosens Bioelectron. 2019 Oct 15;143:111642._x000D_ _x000D_ 8: Shiroishi M, Ito Y, Shimokawa K, Lee JM, Kusakabe T, Ueda T. Structure-_x000D_ function analyses of a stereotypic rheumatoid factor unravel the structural_x000D_ basis for germline-encoded antibody autoreactivity. J Biol Chem. 2018 May_x000D_ 4;293(18):7008-7016._x000D_ _x000D_ 9: Hamilton RG. Rheumatoid factor interference in immunological methods. <a href="https://pubmed.ncbi.nlm.nih.gov/2671691/">Monogr</a>_x000D_ Allergy. 1989;26:27-44._x000D_ _x000D_ <strong>Rheumatoid Factor Removal Kit for Serum and Plasma</strong><a href="https://moleculardepot.com/product-category/research-kits/">: Research Kits</a>