Lasalocid (sodium)

Lasalocid sodium (Lasalocid sodium-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid sodium exhibits antitumor activity. Lasalocid sodium is orally active[1][2][3].

Product Specifications

CAS Number

[25999-20-6]

Product Name Alternative

Lasalocid-A (sodium) ; Ionophore X-537A (sodium) ; Antibiotic X-537A (sodium)

UNSPSC

12352005

Hazard Statement

H225, H302+H312+H332, H319

Target

Antibiotic; Apoptosis; Autophagy; Bacterial; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/Lasalocid-sodium.html

Concentration

10mM

Purity

99.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O[Na])C1=C(CC[C@@H](C)[C@H](O)[C@H](C)C([C@@H]([C@H]2O[C@@]([C@H]3CC[C@](O)(CC)[C@H](C)O3)(CC)C[C@@H]2C)CC)=O)C=CC(C)=C1O

Molecular Formula

C34H53NaO8

Molecular Weight

612.77

Precautions

H225, H302+H312+H332, H319

References & Citations

[1]Chen M, et al. Effect of monensin and lasalocid-sodium on the growth of methanogenic and rumen saccharolytic bacteria. Appl Environ Microbiol. 1979 Jul;38 (1) :72-7.|[2]Kim KY, et al., Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC-3 cells. Biomed Pharmacother. 2017 Apr;88:1016-1024.|[3]OZ HS, et al., Efficacy of lasalocid against murine Pneumocystis carinii pneumonitis. Antimicrob Agents Chemother. 1997 Jan;41 (1) :191-2.