Actinobolin (hemisulfate)
Product Specifications
UNSPSC Description
Actinobolin hemisulfate ((+)-Actinobolin hemisulfate) is the hemisulfate form of Actinobolin (HY-W995025). Actinobolin hemisulfate is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin hemisulfate inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively[1].
Target Antigen
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/actinobolin-hemisulfate.html
Smiles
O=S(O)(O)=O.C[C@H](N)C(N[C@@H]1[C@@]2([H])C(C(O[C@@H]1C)=O)=C(C[C@H]([C@@H]2O)O)O)=O.[1/2]
Molecular Weight
349.35
References & Citations
[1]Tharra PR, et al., Short Synthesis of (+)-Actinobolin: Simple Entry to Complex Small-Molecule Inhibitors of Protein Synthesis. Angew Chem Int Ed Engl. 2022 Apr 19;61(17):e202116520.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W995025A/Actinobolin-hemisulfate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W995025A/
Clinical Information
No Development Reported
CAS Number
18802-17-0
Curated Selection
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