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Actinobolin (hemisulfate)

Product Specifications

UNSPSC Description

Actinobolin hemisulfate ((+)-Actinobolin hemisulfate) is the hemisulfate form of Actinobolin (HY-W995025). Actinobolin hemisulfate is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin hemisulfate inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively[1].

Target Antigen

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/actinobolin-hemisulfate.html

Smiles

O=S(O)(O)=O.C[C@H](N)C(N[C@@H]1[C@@]2([H])C(C(O[C@@H]1C)=O)=C(C[C@H]([C@@H]2O)O)O)=O.[1/2]

Molecular Weight

349.35

References & Citations

[1]Tharra PR, et al., Short Synthesis of (+)-Actinobolin: Simple Entry to Complex Small-Molecule Inhibitors of Protein Synthesis. Angew Chem Int Ed Engl. 2022 Apr 19;61(17):e202116520.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W995025A/Actinobolin-hemisulfate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W995025A/

Clinical Information

No Development Reported

CAS Number

18802-17-0

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