Phorbol 12-tiglate
Phorbol 12-tiglate is a derivative of Phorbol. Phorbol, a hydrolyzed product of Croton oil, promotes tumor development by activating protein kinase C. Phorbol and its derivatives can be used to construct carcinogenic models in biomedical research[1].
Product Specifications
CAS Number
92214-56-7
UNSPSC
12352211
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phorbol-12-tiglate.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@](C2(C)C)([H])[C@@]3([H])[C@]([C@@H]([C@H]1OC(/C(C)=C/C)=O)C)([C@@]4([H])[C@](CC(CO)=C3)(C(C(C)=C4)=O)O)O
Molecular Formula
C25H34O7
Molecular Weight
446.53
References & Citations
[1]Blumberg P M. Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture[J]. Cancer research, 1988, 48 (1) : 1-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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