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Glycodeoxycholic Acid (Standard)

Glycodeoxycholic Acid (Standard) is the analytical standard of Glycodeoxycholic Acid. This product is intended for research and analytical applications. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis[1][2][3].

Product Specifications

CAS Number

360-65-6

UNSPSC

12352211

Target

Autophagy; Endogenous Metabolite; Reference Standards; STAT

Type

Reference Standards

Related Pathways

Autophagy; JAK/STAT Signaling; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/glycodeoxycholic-acid-standard.html

Purity

99.92

Smiles

C[C@@H]([C@]1(CC[C@]2([C@@]3(CC[C@@]4(C[C@@H](CC[C@@]4([C@]3(C[C@@H]([C@@]21C)O)[H])C)O)[H])[H])[H])[H])CCC(NCC(O)=O)=O

Molecular Formula

C26H43NO5

Molecular Weight

449.62

References & Citations

[1]Shi C, et al. Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells. Aging (Albany NY) . 2020 Aug 3;12 (15) :15546-15555.|[2]Vaz AR, et al. Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid. J Neurochem. 2010 Jan;112 (1) :56-65.|[3]Fauzi A, et al. Role of glycodeoxycholic acid to induce acute pancreatitis in Macaca nemestrina. J Med Primatol. 2022 Jun;51 (3) :134-142. doi: 10.1111/jmp.12577. Epub 2022 Mar 20. PMID: 35306662; PMCID: PMC9310849.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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