Sophoraisoflavone A
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].
Product Specifications
CAS Number
117204-81-6
Product Name Alternative
Allolicoisoflavone B
UNSPSC
12352005
Target
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sophoraisoflavone-a.html
Purity
99.33
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=C3C(C=CC(C)(C)O3)=C(O)C=C2)=COC4=CC(O)=CC(O)=C14
Molecular Formula
C20H16O6
Molecular Weight
352.34
References & Citations
[1]Lin Y, et, al. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25 (14) :3706-3713.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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