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Sophoraisoflavone A

Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].

Product Specifications

CAS Number

[117204-81-6]

Product Name Alternative

Allolicoisoflavone B

UNSPSC

12352005

Target

Phosphatase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sophoraisoflavone-a.html

Purity

99.33

Solubility

10 mM in DMSO

Smiles

O=C1C(C2=C3C(C=CC(C)(C)O3)=C(O)C=C2)=COC4=CC(O)=CC(O)=C14

Molecular Formula

C20H16O6

Molecular Weight

352.34

References & Citations

[1]Lin Y, et, al. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25 (14) :3706-3713.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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