NAAD (sodium)

NAAD sodium (Deamido nad sodium), a functional NAD+ precursor, is the substrate of glutamine-dependent NAD+ synthetase. NAAD sodium is used to study the structure of nicotinate mononucleotide adenylyltransferases[1][2].

Product Specifications

CAS Number

[104809-30-5]

Product Name Alternative

Deamido nad (sodium)

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/naad-sodium-salt.html

Purity

99.88

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=P([O-])(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[N+]2=CC=CC(C(O)=O)=C2)OP([O-])(OC[C@H]3O[C@H]([C@@H]([C@@H]3O)O)N4C=NC5=C(N=CN=C45)N)=O.[Na+]

Molecular Formula

C21H25N6NaO15P2

Molecular Weight

686.39

Precautions

H315, H319, H335

References & Citations

[1]Samuel A J Trammell, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun. 2016 Oct 10;7:12948.|[2]J Biol Chem. 2005 Apr 15;280 (15) :15131-40. Ralf Jauch, et al. Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements.