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Phosphodiesterase I

Phosphodiesterase I (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase I acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases[1].

Product Specifications

CAS Number

[9025-82-5]

Product Name Alternative

PDE

UNSPSC

12352204

Hazard Statement

H302-H315-H319-H335

Target

Phosphodiesterase (PDE)

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/phosphodiesterase-i.html

Solubility

10 mM in DMSO

Smiles

[PhosphodiesteraseI]

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Sébastien Delhaye, et al. Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders. Mol Psychiatry. 2021 Sep;26 (9) :4570-4582.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

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