Phospho-PTEN (Ser380/Thr382/383) Rabbit APC Conjugate

<strong>Phospho-PTEN (Ser380/Thr382/383) Rabbit APC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018693_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase, Mutated in multiple advanced cancers 1, MMAC1, Phosphatase and tensin homolog, TEP1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yang Z, Xie C, Xu W, Liu G, Cao X, Li W, Chen J, Zhu Y, Luo S, Luo Z, Lu N. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway Oncotarget. 2015 Oct 13;6(31):31916-26._x000D_ 2: Yang Z, Cao X, Xu W, Xie C, Chen J, Zhu Y, Lu N. Phosphorylation of phosphatase and tensin homolog induced by Helicobacter pylori promotes cell invasion by activation of focal adhesion kinase Oncol Lett. 2018 Jan;15(1):1051-1057._x000D_ 3: Zhao Z, Hu J, Gao X, Liang H, Yu H, Liu S, Liu Z. Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells Oncotarget. 2017 May 2;8(18):30030-30038._x000D_ 4: Noh EM, Lee YR, Chay KO, Chung EY, Jung SH, Kim JS, Youn HJ. Estrogen receptor α induces down-regulation of PTEN through PI3-kinase activation in breast cancer cells Mol Med Rep. 2011 Mar-Apr;4(2):215-9._x000D_ 5: Song P, Wu Y, Xu J, Xie Z, Dong Y, Zhang M, Zou MH. Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner Circulation. 2007 Oct 2;116(14):1585-95._x000D_ 6: Tellios N, Belrose JC, Tokarewicz AC, Hutnik C, Liu H, Leask A, Motolko M, Iijima M, Parapuram SK. TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma Sci Rep. 2017 Apr 11;7(1):812._x000D_ 7: Ghosh G, Misra S, Ray R, Chowdhury SG, Karmakar P. Phospho PTEN mediated dephosphorylation of mitotic kinase PLK1 and Aurora Kinase A prevents aneuploidy and preserves genomic stability Med Oncol. 2023 Mar 17;40(4):119._x000D_ 8: Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI, Youle RJ. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy Nature. 2015 Aug 20;524(7565):309-314._x000D_ 9: Thacker S, Eng C. Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes NPJ Genom Med. 2021 Jun 2;6(1):42._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24751536">10: Kane LA, Lazarou M, Fogel AI, Li Y, Yamano K, Sarraf SA, Banerjee S, Youle RJ. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity J Cell Biol. 2014 Apr 28;205(2):143-53. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-PTEN (Ser380/Thr382/383) Rabbit APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>