Antidiabetic agent 6
Antidiabetic agent 6 (Compound 19) is an antidiabetic Agent. Antidiabetic agent 6 stimulates GLUT4 translocation by activation of the PI3K/AKT-dependent signaling pathway. Antidiabetic agent 6 reduces blood glucose levels in Streptozotocin -induced diabetic rats[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Akt; GLUT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/antidiabetic-agent-6.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(CC(C)(C1)C)NC(C)=C(C2C3=CC=C(C(Cl)=C3)Cl)C(NCCC4=CNC5=C4C=CC=C5)=O
Molecular Formula
C29H29Cl2N3O2
Molecular Weight
522.47
References & Citations
[1]Katiyar S, et al. Design, Synthesis, and Biological Evaluation of 1,4-Dihydropyridine-Indole as a Potential Antidiabetic Agent via GLUT4 Translocation Stimulation. J Med Chem. 2024 Jul 25;67 (14) :11957-11974.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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