Neocryptotanshinone
Product Specifications
UNSPSC Description
Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].
Target Antigen
NF-κB; NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation;NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/neocryptotanshinone.html
Purity
98.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C([C@@H](C)CO)=C(O)C(C2=C1C=CC3=C2CCCC3(C)C)=O
Molecular Weight
314.38
References & Citations
[1]Chuanhong Wu, et al. Neocryptotanshinone Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages by Suppression of NF-κB and iNOS Signaling Pathways. Acta Pharm Sin B. 2015 Jul;5(4):323-9.|[2]H C Lin, et al. Two New Fatty Diterpenoids From Salvia Miltiorrhiza. J Nat Prod. 2001 May;64(5):648-50.|[3]FENG Jinghui, et al. Effects of Salvia miltiorrhiza Bunge extract and its single components on monosodium urate-induced pain in vivo and lipopolysaccharide-induced inflammation in vitro. J Tradit Chin Med. 2021. 41(2): 219-226.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119720/Neocryptotanshinone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119720/Neocryptotanshinone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
109664-02-0
Available Sizes
Curated Selection
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