5-Dehydroepisterol

5-Dehydroepisterol is an episterol derivative and an intermediate in steroid biosynthesis. 5-Dehydroepisterol can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. 5-Dehydroepisterol has anti-fungal activities[1][2].

Product Specifications

CAS Number

[23582-83-4]

UNSPSC

12352211

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/5-dehydroepisterol.html

Purity

92.36

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C=C(C(C)C)CC[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C28H44O

Molecular Weight

396.65

References & Citations

[1]5-Dehydroepisterol. From Wikipedia|[2]Rodrigues JC, et al. Ultrastructural and biochemical alterations induced by 22,26-azasterol, a delta (24 (25) ) -sterol methyltransferase inhibitor, on promastigote and amastigote forms of Leishmania amazonensis.Antimicrob Agents Chemother. 2002 Feb;46 (2) :487-99.