FAM49B (190-198) mouse
FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization[1].
Product Specifications
CAS Number
[1588388-60-6]
UNSPSC
12352209
Target
Ras
Type
Peptides
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fam49b-190-198-mouse.html
Purity
99.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N
Molecular Formula
C49H71N9O14S
Molecular Weight
1042.20
References & Citations
[1]Chattaragada MS, et al. FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. Oncogene. 2018 Feb 8;37 (6) :697-709.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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