FAM49B (190-198) mouse

FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization[1].

Product Specifications

CAS Number

[1588388-60-6]

UNSPSC

12352209

Target

Ras

Type

Peptides

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fam49b-190-198-mouse.html

Purity

99.76

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N

Molecular Formula

C49H71N9O14S

Molecular Weight

1042.20

References & Citations

[1]Chattaragada MS, et al. FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. Oncogene. 2018 Feb 8;37 (6) :697-709.