Stemoninine
Stemoninine is a lycoris alkaloid that can be used as an antitussive. Stemoninine has significant inhibitory activity against human acetylcholinesterase (AChE) (IC50=5.52 μM) [1][2].
Product Specifications
CAS Number
69772-72-1
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/stemoninine.html
Smiles
CC[C@@H]1[C@](C=C2C)(OC2=O)O[C@@](CCC3)([H])[C@@]1([H])[C@@]4([H])N3[C@@]([C@](OC5=O)([H])C[C@@H]5C)([H])CC4
Molecular Formula
C22H31NO5
Molecular Weight
389.49
References & Citations
[1]Peixi Bi, et al. Method of making antitussive medicine and relieving cough. CN1931171A. 2006-09-12|[2]Ramli, et al. "Alkaloids from the roots and leaves of Stichoneuron halabalensis and their acetylcholinesterase inhibitory activities." Natural Product Communications 8.6 (2013) : 1934578X1300800603.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Frequently Asked Questions
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