PDLI3 rabbit pAb
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],
Product Specifications
Background
Gene ID
27295
UniProt
Q53GG5
Cellular Locus
Cytoplasm, myofibril, sarcomere, Z line. Localizes to myofiber Z-lines.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PDLI3 AA range: 251-301
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES14175-1.pdf
Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines.
Gene ID (Human)
27295
SwissProt (Human)
Q53GG5
Available Sizes
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