Nephrin
Product Specifications
CAS Number
[65136-96-1]
UNSPSC Description
Nephrin (Hopane-6α,7β,22-triol) is a cell surface signaling receptor protein with activity in regulating podocyte function. Nephrin plays an important role in the normal function of the kidney's filtration barrier. Nephrin is associated with beta cell survival signals and helps maintain cell survival. Urinary levels of nephrin may be associated with tubular injury and can serve as a biomarker for early acute kidney injury[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nephrin.html
Smiles
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H]4C(C)(O)C)C)C)([H])[C@@]5([C@@](C(C)(CCC5)C)([H])[C@H]([C@@H]1O)O)C
Molecular Weight
460.73
References & Citations
[1]Urinary Nephrin as a Biomarker of Glomerular Maturation and Injury Is Associated with Acute Kidney Injury and Mortality in Critically Ill Neonates
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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