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Relebactam (sodium)

Relebactam sodium (MK-7655 sodium) is a potent and selective β-lactamase inhibitor with the activity of delaying the development of bacterial resistance to antibiotics. Relebactam sodium can bind to a variety of β-lactamases, thereby improving the efficacy of β-lactam antibiotics. Relebactam sodium shows good application potential in inhibiting complicated bacterial infections[1].

Product Specifications

CAS Number

[1502858-91-4]

Product Name Alternative

MK-7655 (sodium)

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/relebactam-sodium.html

Smiles

O=S(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)(O[Na])=O

Molecular Formula

C12H19N4NaO6S

Molecular Weight

370.36

References & Citations

[1]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59 (8) :5029-31.|[2]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46 (5) :483-93.|[3]Imipenem monohydrate/cilastatin sodium/relebactam monohydrate, pretomanid, and elexacaftor/tezacaftor/ivacaftor

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Curated Selection

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