8-Epiloganin

8-Epiloganin can be isolated from Castilleja rubra and has anti-inflammatory properties. 8-Epiloganin inhibits LPS-induced release of pro-inflammatory cytokines, namely tumor necrosis factor-α and interleukin-1β[1].

Product Specifications

CAS Number

[79172-04-6]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/8-epiloganin.html

Solubility

10 mM in DMSO

Smiles

COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])C[C@@H]([C@H]2C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O

Molecular Formula

C17H26O10

Molecular Weight

390.38

References & Citations

[1]Lee DS, et al. Secondary metabolites isolated from Castilleja rubra exert anti-inflammatory effects through NF-κB inactivation on lipopolysaccharide-induced RAW264.7 macrophages. Arch Pharm Res. 2014 Jul;37 (7) :947-54.