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Elritercept

Elritercept (KER-050) is a recombinant fusion protein comprising a modified activin receptor type IIA extracellular domain fused to a human IgG1 Fc. Elritercept inhibits activin A and other select TGF-β superfamily ligands[1][2].

Product Specifications

CAS Number

2727114-26-1

Product Name Alternative

KER-050

UNSPSC

12352203

Target

TGF-beta/Smad

Type

Inhibitory Antibodies

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/elritercept.html

References & Citations

[1]Elritercept|[2]Lachey J, et al. Elritercept, a modified activin receptor IIA ligand trap, increased erythropoiesis and thrombopoiesis in a phase 1 trial. Blood Adv. 2025 Jan 14;9 (1) :193-201.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Frequently Asked Questions

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