TMRE

Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms[1].

Product Specifications

CAS Number

[115532-52-0]

Product Name Alternative

Tetramethylrhodamine ethyl ester perchlorate

UNSPSC

12171500

Hazard Statement

H302+H312, H315, H319

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/TMRE.html

Concentration

10mM

Purity

98.49

Solubility

DMSO : 27.78 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)OCC.O=Cl(=O)([O-])=O

Molecular Formula

C26H27ClN2O7

Molecular Weight

514.95

Precautions

H302+H312, H315, H319

References & Citations

[1]Crowley LC, et al. Measuring Mitochondrial Transmembrane Potential by TMRE Staining. Cold Spring Harb Protoc. 2016 Dec 1;2016 (12) :pdb.prot087361.|[2]Bantseev V, et al. Confocal laser scanning microscopy imaging of dynamic TMRE movement in the mitochondria of epithelial and superficial cortical fiber cells of bovine lenses. Mol Vis. 2005 Jul 14;11:518-23.|[3]Crowley LC, et al. Measuring Mitochondrial Transmembrane Potential by TMRE Staining. Cold Spring Harb Protoc. 2016 Dec 1;2016 (12) :pdb.prot087361.