(S) -Indoximod-d3
(S) -Indoximod-d3 is the deuterium labeled (S) -Indoximod. (S) -Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) . (S) -Indoximod can be used for the research of cancer[1][2][3].
Product Specifications
CAS Number
1801851-87-5
Product Name Alternative
1-Methyl-L-tryptophan-d3; (S) -NLG-8189-d3
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 4.81mg/mL (ultrasonic; warming; adjust pH to 4 with HCl; heat to 60°C)
Smiles
N[C@@H](CC1=CN(C([2H])([2H])[2H])C2=CC=CC=C12)C(O)=O
Molecular Formula
C12H11D3N2O2
Molecular Weight
221.27
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Huang GL, et, al. PEG-Poly (1-Methyl-l-Tryptophan) -Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel) . 2019 May 9;9 (5) :719.|[3]Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143 (6) :1516-1529.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2296903 1.0 µg DNA
ST8SIA6 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details ![CLDN5 Recombinant Monoclonal Antibody [13G6]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
