Azathioprine (Standard)

Azathioprine (Standard) is the analytical standard of Azathioprine. This product is intended for research and analytical applications. Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP) . Azathioprine has myelosuppressive effects and induces apoptosis[1][3].

Product Specifications

CAS Number

[446-86-6]

Product Name Alternative

BW 57-322 (Standard)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335-H340-H350-H360

Target

Apoptosis; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/azathioprine-standard.html

Purity

99.82

Smiles

O=[N+](C1=C(SC2=C3NC=NC3=NC=N2)N(C)C=N1)[O-]

Molecular Formula

C9H7N7O2S

Molecular Weight

277.26

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Patel, A.A., R.A. Swerlick, and C.O. McCall, Azathioprine in dermatology: the past, the present, and the future. J Am Acad Dermatol, 2006. 55 (3) : p. 369-89.|[2]Maltzman, J.S. and G.A. Koretzky, Azathioprine: old drug, new actions. J Clin Invest, 2003. 111 (8) : p. 1122-4.|[3]Dubinsky, M.C., Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol, 2004. 2 (9) : p. 731-43.