Recombinant AMPK Complex (A2+B2+G2) Protein

<strong>Recombinant AMPK Complex (A2+B2+G2) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017549_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 63.7 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Moon S, Han D, Kim Y, Jin J, Ho WK, Kim Y. Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry Sci Rep. 2014 Mar 14;4:4376._x000D_ 2: Rajamohan F, Reyes AR, Frisbie RK, Hoth LR, Sahasrabudhe P, Magyar R, Landro JA, Withka JM, Caspers NL, Calabrese MF, Ward J, Kurumbail RG. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators Biochem J. 2016 Mar 1;473(5):581-92._x000D_ 3: Shay AE, Diwakar BT, Guan BJ, Narayan V, Urban JF Jr, Prabhu KS. IL-4 up-regulates cyclooxygenase-1 expression in macrophages J Biol Chem. 2017 Sep 1;292(35):14544-14555._x000D_ 4: Pelosse M, Cottet-Rousselle C, Grichine A, Berger I, Schlattner U. Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism Exp Suppl. 2016;107:491-523._x000D_ 5: Hubbard JA, Xiao B, Wilson JR. Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1) Methods Mol Biol. 2018;1732:1-14._x000D_ 6: Oakhill JS, Scott JW, Dite TA. Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells Methods Mol Biol. 2018;1732:159-169._x000D_ 7: Zhang D, Tang B, Xie X, Xiao YF, Yang SM, Zhang JW. The interplay between DNA repair and autophagy in cancer therapy Cancer Biol Ther. 2015;16(7):1005-13._x000D_ 8: Scott JW, Norman DG, Hawley SA, Kontogiannis L, Hardie DG. Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate J Mol Biol. 2002 Mar 22;317(2):309-23._x000D_ 9: Woods A, Vertommen D, Neumann D, Turk R, Bayliss J, Schlattner U, Wallimann T, Carling D, Rider MH. Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis J Biol Chem. 2003 Aug 1;278(31):28434-42._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/28302767">10: Willows R, Navaratnam N, Lima A, Read J, Carling D. Effect of different γ-subunit isoforms on the regulation of AMPK Biochem J. 2017 May 9;474(10):1741-1754. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant AMPK Complex (A2+B2+G2) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>