Neuraminidase-IN-20

Neuraminidase-IN-20 (Compound 5i) is a potent inhibitor of mutant neuraminidase (NA) (H5N1-H274Y) (IC50= 0.44 μM) .Neuraminidase-IN-20 binds to the 430 cavity site of NA and disrupts the enzymatic activity of NA[1].

Product Specifications

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/neuraminidase-in-20.html

Solubility

10 mM in DMSO

Smiles

C/C(C1=CC=C(C=C1)NC(CC2=CC=CS2)=O)=N\NC(C3=CC=C(C=C3)F)=O

Molecular Formula

C21H18FN3O2S

Molecular Weight

395.45

References & Citations

[1]Fu SK, et al.Discovery andsynthesis of novel benzoylhydrazone neuraminidase inhibitors. Bioorg Med Chem Lett. 2024 Jun 1;105:129743.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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