FLT3-IN-10
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3) . FLT3-IN-10 has the potential for the research of FLT3-mutated acute myeloid leukemia (AML) [1].
Product Specifications
CAS Number
[2088735-51-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-10.html
Purity
98.80
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC(C=C1)=CC=C1C2=CN=C(NC3=CC=CC=C3)O2
Molecular Formula
C15H11FN2O
Molecular Weight
254.26
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Kim HJ, et al. Discovery of Oxazol-2-amine Derivatives as Potent Novel FLT3 Inhibitors. Molecules. 2020;25 (21) :5154.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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