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FLT3-IN-10

FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3) . FLT3-IN-10 has the potential for the research of FLT3-mutated acute myeloid leukemia (AML) [1].

Product Specifications

CAS Number

[2088735-51-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

FLT3

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/flt3-in-10.html

Purity

98.80

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC(C=C1)=CC=C1C2=CN=C(NC3=CC=CC=C3)O2

Molecular Formula

C15H11FN2O

Molecular Weight

254.26

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Kim HJ, et al. Discovery of Oxazol-2-amine Derivatives as Potent Novel FLT3 Inhibitors. Molecules. 2020;25 (21) :5154.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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