Sarcosinamide chloroethylnitrosourea
Sarcosinamide chloroethylnitrosourea is an orally active alkylating agent. Sarcosinamide chloroethylnitrosourea can induce apoptosis by promoting DNA alkylation. Sarcosinamide chloroethylnitrosourea can be used in cancer-related research[1].
Product Specifications
CAS Number
81965-43-7
Product Name Alternative
SarCNU; Sarmustine
UNSPSC
12352211
Target
Apoptosis; DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sarcosinamide-chloroethylnitrosourea.html
Smiles
O=NN(CCCl)C(N(CC(N)=O)C)=O
Molecular Formula
C6H11ClN4O3
Molecular Weight
222.63
References & Citations
[1]Skalski V, et al. The cytotoxicity of sarcosinamide chloroethylnitrosourea (SarCNU) and BCNU in primary gliomas and glioma cell lines: analysis of data in reference to theoretical peak plasma concentrations in man. Cancer Chemother Pharmacol. 1988;22 (2) :137-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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