Tur1A

Tur1A is an antimicrobial peptide derived from bottlenose dolphins Tursiops truncates. Tur1A inhibits bacterial protein synthesis by binding to ribosomes and blocking the transition from the initiation stage to the extension stage[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tur1a.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CC(C)C)C(N5[C@@H](CCC5)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N7[C@@H](CCC7)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC8=CC=CC=C8)C(N9[C@@H](CCC9)C(N%10[C@@H](CCC%10)C(N%11[C@@H](CCC%11)C(N[C@@H](CC%12=CC=CC=C%12)C(N%13[C@@H](CCC%13)C(N[C@@H]([C@@H](C)CC)C(N%14[C@@H](CCC%14)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N%15[C@@H](CCC%15)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N%16[C@@H](CCC%16)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C188H300N62O34

Molecular Weight

3972.79

References & Citations

[1]Mardirossian M, et al. The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chem Biol. 2018 May 17;25 (5) :530-539.e7.