VU6007496
VU6007496 is a highly selective and CNS penetrant M1 positive allosteric modulator (PAM) . VU6007496 shows excellent pharmacokinetics (PK) [1].
Product Specifications
CAS Number
2127101-85-1
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu6007496.html
Smiles
O=C(NC1CCOCC1)C2=NC(C=CN3C)=C3C(CC4=CC=C(C5=NN(C)C=C5)C=C4)=C2
Molecular Formula
C25H27N5O2
Molecular Weight
429.51
References & Citations
[1]Engers JL, et al. Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate. ACS Chem Neurosci. 2024 Aug 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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