RG 14921
RG 14921 is a compound structurally related to Erbstatin and has inhibitory activity against EGFR tyrosine kinase and CAMP-dependent kinase activity. RG 14921 inhibits EGF receptor kinase activity as a noncompetitive inhibitor.
Product Specifications
CAS Number
144909-21-7
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rg-14921.html
Smiles
O=C1C=CC(C2=CC(O)=CC=C2O)=CN1
Molecular Formula
C11H9NO3
Molecular Weight
203.19
References & Citations
[1]INHIBITION KINETICS AND SELECTIVITY OF THE TYROSINE KINASE INHIBITOR ERBSTATIN AND A PYRIDONE-BASED ANALOGUE
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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