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Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal

Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal, a glucocorticoid receptor agonist, is a drug-linker conjugate for ADC. Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal can be used to synthesize the anti-CD40 antibody agent conjugates (WO2019106608A1; example 9) [1].

Product Specifications

CAS Number

2345732-83-2

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Glucocorticoid Receptor

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glucocorticoid-receptor-agonist-1-phosphate-gly-glu-mal.html

Purity

99.86

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=P(O)(O)OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC(NC([C@H](CCC(O)=O)NC(CN8C(C=CC8=O)=O)=O)=O)=CC=C7)O2)C)=O

Molecular Formula

C46H50N3O15P

Molecular Weight

915.87

References & Citations

[1]Hobson A D, et al. Anti-cd40 antibody drug conjugates. World Intellectual Property Organization. WO2019106608A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Frequently Asked Questions

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