DiMNF

DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent[1].

Product Specifications

CAS Number

[14756-24-2]

Product Name Alternative

3',4'-Dimethoxy-αNF

UNSPSC

12352005

Hazard Statement

H301

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dimnf.html

Concentration

10mM

Purity

98.46

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 70°C)

Smiles

O=C1C2=CC=C3C=CC=CC3=C2OC(C4=CC=C(OC)C(OC)=C4)=C1

Molecular Formula

C21H16O4

Molecular Weight

332.35

Precautions

H301

References & Citations

[1]Murray IA, et al. Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Mol Pharmacol. 2011 Mar;79 (3) :508-19.