DiMNF
DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent[1].
Product Specifications
CAS Number
14756-24-2
Product Name Alternative
3',4'-Dimethoxy-αNF
UNSPSC
12352005
Hazard Statement
H301
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dimnf.html
Concentration
10mM
Purity
98.46
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C1C2=CC=C3C=CC=CC3=C2OC(C4=CC=C(OC)C(OC)=C4)=C1
Molecular Formula
C21H16O4
Molecular Weight
332.35
Precautions
H301
References & Citations
[1]Murray IA, et al. Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Mol Pharmacol. 2011 Mar;79 (3) :508-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
12947064 1.0 µg DNA
B430306N03Rik Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 