Vinzolidine
Product Specifications
UNSPSC Description
Vinzolidine is a semisynthetic derivative of the catharanthus alkaloid. Vinzolidine exerts its cytotoxic effect on tumor cells by interfering with microtubulin polymerization, thereby inhibiting cell division. Vinzolidine can be utilized in research to investigate synergistic effects when combined with other chemotherapeutic agents or biologic therapies, as well as to study cancer cells' tolerance or resistance to these treatments, and to explore approaches to overcome such obstacles[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vinzolidine.html
Smiles
CC[C@]1(O)C[C@H]2C[C@@](C3=C(OC)C=C4C([C@]56CCN7[C@H]5[C@@]([C@@H](OC(C)=O)[C@]8(C(N(CCCl)C(O8)=O)=O)[C@@H]6N4C)(CC)C=CC7)=C3)(C(OC)=O)C9=C(C%10=CC=CC=C%10N9)CCN(C1)C2
Molecular Weight
884.46
References & Citations
[1]Aapro M S, et al. Interactions of human leukocyte interferon with vinca alkaloids and other chemotherapeutic agents against human tumors in clonogenic assay[J]. Cancer Chemotherapy and Pharmacology, 1983, 10: 161-166.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106072/Vinzolidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106072/
Clinical Information
No Development Reported
CAS Number
67699-40-5
Curated Selection
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